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KMID : 1007520130220061717
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Food Science and Biotechnology
2013 Volume.22 No. 6 p.1717 ~ p.1724
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Quality Characteristics of Cheonggukjang Containing Phellinus linteus Extracts and Antitumor Effects in Hep-2 and SK-MES Cells
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Jiang Cheng-Kui
Lee Kyung-Ah
Kim Cheon-Jei
Lee Joo-Yeon
Hur Sun-Jin
Lee Si-Kyung
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Abstract
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The quality characteristics of cheonggukjang containing Phellinus linteus extracts (PLE) and its cytotoxicity in Hep-2 and SK-MS-cells were investigated. Cheonggukjang containing 0.3% PLE showed the highest protease activity (7th aging day). The reducing sugar content and the amylase activity of cheonggukjang supplemented with 0.3% PLE increased immediately on the 1st aging day, and decreased slightly until the 15th aging day. All samples showed an increase in the amino-type nitrogen content. The dominant volatile compound detected using chromatography-mass spectrophotometry was 2,5-dimethyl pyrazine with the highest peak area value of 17.36% observed in cheonggukjang containing 0.3% PLE (3rd aging day). Cheonggukjang containing 0.3% PLE exhibited the best taste and acceptability with the least unpleasant odor. Cheonggukjang supplemented with PLE had a higher antitumor activity against SK-MES-1 and Hep-2 cells than a control. Hep-2 cells treated with a 10 mg/mL extract of cheonggukjang containing 0.3% PLE showed the highest growth inhibition rate of 84.74%.
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KEYWORD
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cheonggukjang, Phellinus linteus extract, Amino-type N, volatile compounds, cytotoxicity
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